Everything about ceesdekker
Everything about ceesdekker
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Halfway as a result of his profession, Cees Dekker reinvented himself. After several years of hardcore physics, he shifted his target to ‘nanobiology’ within the change of your millennium. A phrase he coined himself, to be a issue of point.
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules
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Considering the fact that 2000, Dekker has shifted the key concentration of his function in direction of biophysics where by he research the properties of solitary biomolecules and cells using the instruments of nanotechnology. This alteration of area was driven by his fascination for that extraordinary functioning of biological molecular constructions, and also because of the long-term viewpoint that lots of attention-grabbing discoveries can be expected On this area.[5] Recent traces of exploration in his biophysics team are during the parts of:[six]
This yielded a breakthrough. Within just only a few months, we ended up capable of evaluate transport by a person one-walled carbon nanotube. Depending on small-temperature experiments by an excellent PhD university student in my group, Sander Tans (now a valued colleague and professor at Delft University of Technological innovation with an Energetic investigate lab at AMOLF in Amsterdam), we showed that carbon nanotubes were being genuine quantum wires with incredibly lengthy (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic conduct.
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of a single wire bridging two electrodes
‘Initially we checked out Organic methods by using a Actual physical see and acted on The idea with the tools we knew. It took a several years right before we started Doing work extra on the massive Organic issues. I then started to phone it nanobiology, a expression that didn't exist at some time.
2011, first in vitro measurements of transportation throughout just one biomimetic nuclear pore complicated; development of multiplexed magnetic tweezers for kilo-molecule experiments; and fixed the system of homology recognition in DNA homologous recombination
2003, shown the initial biosensors created out of a carbon nanotube; resolved the composition and system of DNA fix proteins; and discovery of a fresh method for fabricating solid-point out nanopores for DNA translocation
Quite cool, but that wasn’t actually where by my interest lay. I wished to pioneer And that i had the feeling that was ceesdekker.net no more probable, because the most exciting essential insights experienced currently been uncovered. But my discipline experienced developed numerous enjoyable new applications to evaluate person molecules. I decided that I planned to utilize this to biology, to look at it from a physical perspective.’
FtsZ treadmilling is important for Z-ring condensation and septal constriction initiation in bacterial mobile division
Later on we spoke yet again briefly because Dekker felt that our discussion of his faith speedily turned purely philosophical, Whilst it also concretely assists him in his operate.
Allow’s 1st glance again at the moment whenever you decided to shift your concentrate from superconductivity and nanotubes to biology at the end of the 1990s.
2013, controlled shaping of Are living bacterial cells into arbitrary designs; and discovery of spontaneous fluctuations during the handedness of histone tetrasomes